Lot numbers can be found on the outside label of a product:
6-Fluoro-1H-indazole-5-carbonitrile
-
CAS No. 633327-11-4
- Cat. No. CS-0050207
- Purity≥95%
- MDL No.MFCD17010087
*For research and further manufacturing use only, not for direct human use.
Structure of 633327-11-4
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 633327-11-4
- Cat. No. CS-0050207
- Purity ≥95%
- MDL No. MFCD17010087
- Storage Store at room temperature
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₈H₄FN₃
- Molecular Weight None
- Synonym(s) 1h-indazole-5-carbonitrile,6-fluoro
- SMILES FC1=CC2=C(C=NN2)C=C1C#N
Description
6-Fluoro-1H-indazole-5-carbonitrile features a fluorinated indazole core with a nitrile group at the 5-position, enabling integration into diverse heterocyclic scaffolds. This electron-deficient system enhances reactivity in cross-coupling and cyclization processes. The compound exhibits bench-stable handling characteristics and compatibility with standard synthetic protocols.
Application
6-Fluoro-1H-indazole-5-carbonitrile serves as a versatile building block in medicinal chemistry, enabling efficient access to functionalized heterocyclic scaffolds. The nitrile group facilitates nucleophilic additions and cyclizations, while the fluorine substituent enhances metabolic stability and modulates electronic properties. This compound exhibits excellent bench stability and compatibility with standard coupling reactions, making it well-suited for parallel synthesis and API development workflows.
Synthesis
-
References
-
GLAXO GROUP LIMITED; BAILEY, James; KING, Nigel Paul; LIN, Xichen; REN, Feng; TAN, Kheng-Chuan; MAK, Sing Yeung Patent: WO2011/72488 A1, 2011 ; Location in patent: Page/Page column 17; 39 ; WO 2011/072488 A1
-
-
Route2
-
557-21-1 -
In-stock
105391-70-6 - ~%
-
In-stock
633327-11-4
References
-
GLAXO GROUP LIMITED; BAILEY, James; KING, Nigel Paul; LIN, Xichen; REN, Feng; TAN, Kheng-Chuan; MAK, Sing Yeung Patent: WO2011/72488 A1, 2011 ; Location in patent: Page/Page column 17; 39-40 ; WO 2011/072488 A1
-
-
Route3
-
In-stock
633327-10-3 - ~%
-
In-stock
633327-11-4
References
-
Eisai Co., Ltd. Patent: EP1510516 A1, 2005 ; Location in patent: Page/Page column 85 ;
-
Safety Information
Download SDS|
GHS Pictogram :
N/A
|
GHS No : N/A
|
|
Signal Word : N/A
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : N/A
|
|
|
Precautionary Statements : N/A
|
|
Quality Control
Computational Chemistry Data
- TPSA 52.47
- LogP 1.57368
- H_Acceptors 2
- H_Donors 1
- Rotatable_Bonds 0
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 6-Fluoro-1H-indazole-5-carbonitrile sigma6-Fluoro-1H-indazole-5-carbonitrile manufacturer6-Fluoro-1H-indazole-5-carbonitrile price6-Fluoro-1H-indazole-5-carbonitrile structure6-Fluoro-1H-indazole-5-carbonitrile SDSbuy 6-Fluoro-1H-indazole-5-carbonitrile6-Fluoro-1H-indazole-5-carbonitrile supplier6-Fluoro-1H-indazole-5-carbonitrile uses6-Fluoro-1H-indazole-5-carbonitrile molecular weightprice of 6-Fluoro-1H-indazole-5-carbonitrile6-Fluoro-1H-indazole-5-carbonitrile chemical name formula of 6-Fluoro-1H-indazole-5-carbonitrile