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CS-W001157 4
Total: USD 88.00

2-Methoxy-N-methylaniline

  • CAS No. 10541-78-3

  • Cat. No. CS-0151024
  • Purity≥98%
  • MDL No.MFCD03093822

*For research and further manufacturing use only, not for direct human use.

2-Methoxy-N-methylaniline|CS-0151024

Structure of 10541-78-3

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General Information

  • CAS No. 10541-78-3
  • Cat. No. CS-0151024
  • Purity ≥98%
  • MDL No. MFCD03093822
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₁NO
  • Molecular Weight 137.18
  • Synonym(s) O-METHOXY-N-METHYLANILINE
  • SMILES CNC1=CC=CC=C1OC

Description

2-Methoxy-N-methylaniline features a methoxy group at the ortho position and a methylamino substituent, delivering enhanced electron density and improved solubility in organic media. This combination enables efficient coupling in cross-coupling reactions and facilitates direct functionalization in synthetic pathways requiring moderate nucleophilicity and stability under standard conditions.

Synthesis

  • Route1
    • null|null
      50-00-0
    • null|null
      90-04-0
    • ~64%
    • In-stock
      2-Methoxy-N-methylaniline|CS-0151024
      10541-78-3

    References

    • Barluenga, Jose; Bayon, Ana M.; Asensio, Gregorio Journal of the Chemical Society, Chemical Communications, 1984 , # 20 p. 1334 - 1335
  • Route2
    • null|null
      23896-88-0
    • null|null
      90-04-0
    • ~%
    • In-stock
      2-Methoxy-N-methylaniline|CS-0151024
      10541-78-3

    References

    • US6245799 B1, ; US 6245799 B1
  • Route3
    • In-stock
      Methylboronic acid|CS-W018525
      13061-96-6
    • null|null
      90-04-0
    • ~66%
    • In-stock
      2-Methoxy-N-methylaniline|CS-0151024
      10541-78-3

    References

    • Gonzalez, Israel; Mosquera, Jesus; Guerrero, Cesar; Rodriguez, Ramon; Cruces, Jacobo Organic Letters, 2009 , vol. 11, # 8 p. 1677 - 1680

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H317
Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P501

Quality Control

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Computational Chemistry Data

  • TPSA   21.26
  • LogP   1.7369
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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