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Structure of 1056264-22-2
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4-Bromo-5-fluoro-1H-indazole is a heterocyclic building block featuring complementary halogen handles for late-stage functionalization. The bromine and fluorine substituents enable orthogonal cross-coupling reactions, while the indazole core provides enhanced metabolic stability and π-stacking potential in bioactive molecule design.
4-Bromo-5-fluoro-1H-indazole serves as a versatile heterocyclic building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The bromo group facilitates Suzuki, Stille, and Negishi couplings, while the fluoro substituent enhances metabolic stability and modulates electronic properties. Its bench-stable nature and compatibility with diverse reaction conditions make it ideal for constructing complex pharmaceutical scaffolds and functionalized biaryls.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H319-H335
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: