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CS-W001157 4
Total: USD 88.00

Piperazine-2,5-dione

  • CAS No. 106-57-0

  • Cat. No. CS-0046695
  • Purity≥97%
  • MDL No.MFCD00006009

*For research and further manufacturing use only, not for direct human use.

Piperazine-2,5-dione|CS-0046695

Structure of 106-57-0

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General Information

  • CAS No. 106-57-0
  • Cat. No. CS-0046695
  • Purity ≥97%
  • MDL No. MFCD00006009
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₆N₂O₂
  • Molecular Weight 114.10
  • Synonym(s) Glycocoll Anhydride
  • SMILES O=C(CN1)NCC1=O

Application

Piperazine-2,5-dione serves as a versatile scaffold in medicinal chemistry, enabling the construction of diverse heterocyclic systems through standard functionalization protocols. Its inherent stability and compatibility with common synthetic transformations facilitate efficient access to biologically relevant architectures. The molecule functions as a key building block for peptide mimetics and pharmacophores, offering predictable reactivity and ease of purification in multi-step synthesis.

Synthesis

  • Route1
    • Methyl glycinate|CS-0454289
      616-34-2
    • ~%
    • In-stock
      Piperazine-2,5-dione|CS-0046695
      106-57-0

    References

    • Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, , p. 1484;engl.Ausg.S.1431
  • Route2
    • null|null
      44234-35-7
    • H-Gly-Oet|CS-0636597
      459-73-4
    • ~%
    • In-stock
      Piperazine-2,5-dione|CS-0046695
      106-57-0
    • null|null
      64222-26-0

    References

    • Justus Liebigs Annalen der Chemie, , vol. 607, p. 174,178
  • Route3
    • null|null
      51110-48-6
    • ~%
    • In-stock
      Piperazine-2,5-dione|CS-0046695
      106-57-0

    References

    • Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, , vol. 176, p. 106

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   58.2
  • LogP   -1.7676
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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