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Structure of 1060804-19-4
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4-Fluoropyridin-3-amine serves as a key nitrogen-containing building block in medicinal chemistry, featuring a fluorinated pyridine core that enhances metabolic stability and modulates electronic properties. The amine group enables direct coupling reactions, while the fluorine substituent improves membrane permeability and target binding affinity. This compound integrates efficiently into diverse heterocyclic frameworks for drug discovery applications.
4-Fluoropyridin-3-amine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its ortho-fluoro substitution. The amine functionality facilitates direct derivatization and salt formation, while the pyridine core provides robust hydrogen-bonding capacity and favorable electronic properties for target engagement. Bench-stable and compatible with standard purification protocols, it functions effectively in the synthesis of kinase inhibitors and other bioactive heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: