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Structure of 1060806-60-1
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4-Chloro-6-methoxynicotinic acid features a strategically positioned chloro group and methoxy substituent on the nicotinic acid scaffold, enabling precise tuning of electronic properties and solubility. This configuration supports efficient integration into bioactive scaffolds and synthetic intermediates requiring balanced polarity and metabolic stability under standard conditions.
4-Chloro-6-methoxynicotinic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-chloro and meta-methoxy substituents provide orthogonal reactivity for palladium-catalyzed couplings and selective derivatization. The carboxylic acid functionality facilitates amide formation and esterification, while the compound exhibits good bench stability and ease of purification, making it well-suited for scalable synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: