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Structure of 605661-81-2
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4-Chloro-2-methoxynicotinic acid features a strategically positioned chloro group and methoxy substituent on the nicotinic acid scaffold, enabling precise tuning of electronic properties and solubility. This configuration supports efficient coupling in synthetic routes to bioactive heterocycles and pharmaceutical intermediates under standard conditions.
4-Chloro-2-methoxynicotinic acid serves as a versatile building block for heterocyclic synthesis, particularly in the construction of pyridine and quinoline derivatives. Its ortho-methoxy and meta-chloro substituents enable selective functionalization and compatibility with palladium-catalyzed cross-coupling reactions. The carboxylic acid group facilitates direct amidation or esterification, while the molecule exhibits good bench stability and ease of purification, making it well-suited for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: