6-Bromo-3-chloropyridin-2-amine

Name: 6-Bromo-3-chloropyridin-2-amine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1060815-73-7
Cat. No. CS-0097705
Purity≥95%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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6-Bromo-3-chloropyridin-2-amine|CS-0097705

Structure of 1060815-73-7

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Description

6-Bromo-3-chloropyridin-2-amine is a heteroaromatic building block featuring bromo and chloro substituents at distinct positions on the pyridine ring, enabling selective cross-coupling reactions. The amino group provides a handle for further functionalization, while the electron-withdrawing halogens enhance reactivity in palladium-catalyzed transformations. This compound exhibits good stability under standard conditions and serves as a key intermediate in the synthesis of bioactive molecules and pharmaceutical candidates.

Application

6-Bromo-3-chloropyridin-2-amine serves as a versatile building block in medicinal chemistry, enabling direct functionalization via palladium-catalyzed cross-coupling reactions. The bromo and chloro substituents offer orthogonal reactivity for sequential derivatization, while the pyridin-2-amine moiety provides a handle for further modification. Its bench-stable nature and compatibility with standard synthetic protocols facilitate efficient access to complex heterocyclic scaffolds relevant to API development.

General Information

CAS No. 1060815-73-7
Cat. No. CS-0097705
Purity ≥95%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₄BrClN₂
Molecular Weight 207.46
Synonym(s) 2-Amino-6-bromo-3-chloropyridine
SMILES NC1=NC(Br)=CC=C1Cl

Computational Chemistry Data

TPSA 38.91
LogP 2.0797
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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6-Bromo-3-chloropyridin-2-amine

CAS No. 1060815-73-7

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