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Structure of 1064194-10-0
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N-Boc-3-bromoazetidine features a strained four-membered azetidine ring bearing a bromine atom at the 3-position and a Boc-protected amine at nitrogen. This electrophilic scaffold enables direct incorporation into complex heterocycles via palladium-catalyzed cross-coupling, offering high reactivity under mild conditions. The Boc group ensures stability during storage and handling, while the bromide facilitates downstream functionalization.
N-Boc-3-bromoazetidine serves as a versatile building block in medicinal chemistry, enabling efficient construction of azetidinyl scaffolds via palladium-catalyzed cross-coupling reactions. The bromide functionality facilitates reliable C–C and C–heteroatom bond formation, while the Boc group ensures stability and ease of deprotection under mild acidic conditions. Its small-ring strain enhances reactivity in nucleophilic substitution processes, making it well-suited for rapid diversification in lead optimization campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: