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Bis(triphenylphosphine)copper(1+) nitrate

  • CAS No. 106678-35-7

  • Cat. No. CS-0035149
  • Molecule weight650.12
  • Purity≥98%
  • MDL No.MFCD02091690

*For research and further manufacturing use only, not for direct human use.

Bis(triphenylphosphine)copper(1+) nitrate|CS-0035149

Structure of 106678-35-7

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General Information

  • CAS No. 106678-35-7
  • Cat. No. CS-0035149
  • Purity ≥98%
  • MDL No. MFCD02091690
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₆H₃₀CuNO₃P₂
  • Molecular Weight 650.12
  • Synonym(s) BIS(TRIPHENYLPHOSPHINE)COPPER (I) NITRATE
  • SMILES [O-][N+]([O-])=O.C1([P](C2=CC=CC=C2)(C3=CC=CC=C3)[Cu+][P](C4=CC=CC=C4)(C5=CC=CC=C5)C6=CC=CC=C6)=CC=CC=C1

Description

Bis(triphenylphosphine)copper(I) nitrate serves as a stable, moisture-tolerant source of Cu(I) in catalytic transformations. The copper center, coordinated by two bulky triphenylphosphine ligands, resists oxidation while facilitating efficient coupling reactions under mild conditions. This complex integrates seamlessly into cross-coupling and C–H functionalization protocols where precise control over oxidation state is critical.

Application

Bis(triphenylphosphine)copper(I) nitrate serves as a highly effective, bench-stable catalyst for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions. It enables efficient formation of 1,2,3-triazoles under mild conditions with excellent functional group tolerance. The complex facilitates rapid, high-yielding coupling in both solution-phase and solid-phase synthesis, offering improved handling and reproducibility compared to in situ generated Cu(I) species.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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Computational Chemistry Data

  • TPSA   66.2
  • LogP   6.1126
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   8

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