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Bromo(1,10-phenanthroline)(triphenylphosphine)copper(I)

  • CAS No. 25753-84-8

  • Cat. No. CS-0087776
  • Molecule weight585.94
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Bromo(1,10-phenanthroline)(triphenylphosphine)copper(I)|CS-0087776

Structure of 25753-84-8

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General Information

  • CAS No. 25753-84-8
  • Cat. No. CS-0087776
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₀H₂₃BrCuN₂P
  • Molecular Weight 585.94
  • Synonym(s) BROMO(1,10-PHENANTHROLINE)(TRIPHENYLPHOSPHINE)COPPER (I)
  • SMILES Br[Cu]1([P](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)[N]5=CC=CC6=CC=C7C([N]1=CC=C7)=C65

Description

Bromo(1,10-phenanthroline)(triphenylphosphine)copper(I) features a copper(I) center coordinated by a chelating 1,10-phenanthroline ligand and a triphenylphosphine moiety, delivering enhanced stability and selectivity in cross-coupling reactions. This air-stable complex enables efficient C–C and C–heteroatom bond formation under mild conditions.

Application

Bromo(1,10-phenanthroline)(triphenylphosphine)copper(I) serves as a stable, bench-ready copper(I) source for catalytic C–H functionalization and coupling reactions. It facilitates efficient Ullmann-type couplings and azide-alkyne cycloadditions with high functional group tolerance. The ligand framework enhances reactivity while maintaining ease of handling, making it well-suited for scalable synthesis of heterocyclic scaffolds and complex molecular architectures in medicinal chemistry workflows.

Synthesis

  • Route1

    References

    • University of Massachusetts Patent: US7473797 B2, 2009 ; Location in patent: Page/Page column 15 ;
  • Route2

    References

    • Monica, Girolamo La; Angaroni, M. Angela; Cariati, Franco; Cenini, Sergio Inorganica Chimica Acta, 1988 , vol. 143, p. 239 - 246
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      114632-08-5
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    • In-stock
      Bromo(1,10-phenanthroline)(triphenylphosphine)copper(I)|CS-0087776
      25753-84-8

    References

    • Monica, Girolamo La; Angaroni, M. Angela; Cariati, Franco; Cenini, Sergio Inorganica Chimica Acta, 1988 , vol. 143, p. 239 - 246

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   N/A
  • LogP   N/A
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   N/A

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