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Structure of 1072004-32-0
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Methyl 3-fluoro-5-hydroxybenzoate features a strategically positioned fluorine atom and hydroxyl group on the aromatic ring, enabling precise tuning of electronic properties and hydrogen-bonding capacity. This combination enhances solubility and reactivity in synthetic transformations, particularly in cross-coupling and derivatization workflows. The methyl ester serves as a stable handle for further functionalization under standard conditions.
Methyl 3-fluoro-5-hydroxybenzoate serves as a versatile building block for the synthesis of bioactive heterocycles and pharmaceutical intermediates. The ortho-fluoro and meta-hydroxyl groups enable directed metalation and selective functionalization, while the methyl ester facilitates downstream transformations. Its bench-stable nature and compatibility with common coupling reactions support efficient access to complex scaffolds in medicinal chemistry workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: