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Structure of 403-19-0
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2-Fluoro-4-nitrophenol features a fluorine atom at the ortho position and a nitro group at the para position relative to the phenolic hydroxyl, creating a strongly electron-deficient aromatic system. This combination enhances reactivity in nucleophilic substitution processes and enables straightforward functionalization under mild conditions. The compound exhibits good bench stability and solubility in common organic solvents, facilitating its use in synthetic transformations and as an intermediate in pharmaceutical and agrochemical development.
2-Fluoro-4-nitrophenol serves as a versatile building block in synthetic organic chemistry, enabling direct electrophilic substitution and nucleophilic aromatic substitution reactions due to the strong electron-withdrawing nitro group ortho to the fluorine. Its bench-stable nature and compatibility with diverse coupling processes facilitate efficient access to functionalized heterocycles and pharmaceutical intermediates.
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GHS No : GHS05,GHS07,GHS09
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Signal Word : Danger
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UN#: 3077
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Class : 9
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H317-H318-H410
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Precautionary Statements : P261-P264-P270-P272-P273-P280-P302+P352-P330-P362+P364-P391-P501
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Lot numbers can be found on the outside label of a product: