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Structure of 1073182-86-1
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3-Amino-4,6-dichloropicolinonitrile features a strategically positioned amino group flanked by chlorine substituents and a nitrile moiety on a picolinonitrile core. This electron-deficient heterocycle serves as a high-reactivity scaffold for transition-metal-catalyzed cross-coupling reactions and direct functionalization. The molecule exhibits bench-stable handling characteristics under standard conditions and integrates readily into complex molecular architectures.
3-Amino-4,6-dichloropicolinonitrile serves as a versatile building block in medicinal chemistry, enabling efficient construction of heterocyclic scaffolds via nucleophilic substitution and cyclization reactions. The amino and nitrile groups provide orthogonal reactivity, while the dichloro substituents facilitate regioselective functionalization. Its bench-stable nature and compatibility with standard synthetic protocols make it well-suited for iterative synthesis workflows in API development.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: