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Structure of 107867-51-6
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5-(Trifluoromethyl)pyridine-2,3-diamine features a pyridine core functionalized with a trifluoromethyl group and two adjacent amino substituents, delivering enhanced electron density and improved solubility in polar solvents. This arrangement supports efficient coupling reactions and facilitates incorporation into bioactive scaffolds. The diamine moiety enables versatile coordination in metal complexes, while the trifluoromethyl group imparts metabolic stability and modulates lipophilicity. This compound serves as a key building block for pharmaceutical intermediates and advanced ligands.
5-(Trifluoromethyl)pyridine-2,3-diamine serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles through standard coupling and cyclization reactions. Its dual amine functionality and electron-withdrawing trifluoromethyl group provide enhanced solubility, metabolic stability, and favorable electronic properties for target-directed drug discovery. The compound exhibits good bench stability and compatibility with common protecting group strategies, facilitating efficient purification and integration into complex molecular architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: