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Structure of 107873-03-0
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This difluorinated cyclopropane carboxylic acid features a strained three-membered ring with two fluorine atoms at the geminal position, conferring enhanced metabolic stability and unique electronic properties. The carboxylic acid group enables direct functionalization or salt formation, facilitating integration into bioactive molecules. Its rigid, electron-deficient structure makes it valuable for probing steric and electronic effects in medicinal chemistry and agrochemical design.
2,2-Difluorocyclopropanecarboxylic acid serves as a valuable building block in medicinal chemistry, enabling the introduction of a rigid, electron-withdrawing difluoromethylene group into bioactive scaffolds. Its cyclopropane core imparts conformational constraint, while the carboxylic acid functionality facilitates direct derivatization or coupling reactions. The molecule exhibits good bench stability and is compatible with standard synthetic workflows, making it a practical choice for constructing fluorinated heterocycles and drug-like molecules requiring enhanced metabolic stability.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: