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Structure of 156816-78-3
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2-Fluorocyclopropanecarboxylic acid features a strained cyclopropane ring bearing a fluorine atom and a carboxylic acid group, enabling unique steric and electronic properties. This configuration imparts enhanced metabolic stability and conformational rigidity, making it valuable for medicinal chemistry applications. The molecule exhibits favorable solubility and handles well under standard bench conditions.
2-Fluorocyclopropanecarboxylic acid serves as a valuable building block in medicinal chemistry, enabling the incorporation of a strained cyclopropane motif with a polar carboxylic acid group. Its enhanced metabolic stability and conformational rigidity facilitate target engagement in bioactive molecule design. The fluorine substituent modulates electronic properties and lipophilicity, while the carboxylic acid enables direct derivatization via amide formation or esterification—key steps in peptide and small-molecule synthesis. Bench-stable and compatible with standard reaction conditions, it supports efficient downstream functionalization in both academic and industrial R&D workflows.
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GHS Pictogram :
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GHS No : GHS05,GHS07
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H302-H314-H335
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Precautionary Statements : P260-P264-P270-P271-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: