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CS-W001157 4
Total: USD 88.00

1-Bromo-3-chlorobenzene

  • CAS No. 108-37-2

  • Cat. No. CS-W010720
  • Molecule weight191.46
  • Purity≥98%
  • MDL No.MFCD00000568

*For research and further manufacturing use only, not for direct human use.

1-Bromo-3-chlorobenzene|CS-W010720

Structure of 108-37-2

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General Information

  • CAS No. 108-37-2
  • Cat. No. CS-W010720
  • Purity ≥98%
  • MDL No. MFCD00000568
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄BrCl
  • Molecular Weight 191.46
  • Synonym(s) 3-Chlorobromobenzene
  • SMILES ClC1=CC=CC(Br)=C1

Description

1-Bromo-3-chlorobenzene undergoes bromine-magnesium exchange reactions with i-PrMgCl-LiCl in THF at 0C and is strongly accelerated by electron-withdrawing substituents. It acts as test substrate to study the application of a new catalytic system for cyanation of various aryl halides using K4[Fe(CN)6] as cyanating source.

Synthesis

  • Route1
    • null|null
      456-39-3
    • ~99%
    • In-stock
      1-Bromo-3-chlorobenzene|CS-W010720
      108-37-2

    References

    • Synthesis, , # 16 p. 2534 - 2538
  • Route2

    References

    • Angewandte Chemie - International Edition, , vol. 51, # 49 p. 12303 - 12306 Angew. Chem., , vol. 124, # 49 p. 12469 - 12472,4
  • Route3
    • null|null
      108-42-9
    • ~%
    • In-stock
      1-Bromo-3-chlorobenzene|CS-W010720
      108-37-2

    References

    • Journal of the American Chemical Society, , vol. 69, p. 1221

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H227-H315-H319
Precautionary Statements : P210-P264-P280-P302+P352-P362-P370+P378-P501

Quality Control

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Computational Chemistry Data

  • TPSA   0
  • LogP   3.1025
  • H_Acceptors   0
  • H_Donors   0
  • Rotatable_Bonds   0

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