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Structure of 1083326-75-3
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N-[2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl]methanesulfonamide features a boronate ester group enabling reliable Suzuki-Miyaura cross-coupling under mild conditions. The methanesulfonamide moiety enhances solubility and stability, while the 2-methoxy-pyridine scaffold provides favorable electronic properties for transition-metal catalysis. This reagent integrates efficiently into complex molecule synthesis workflows.
N-[2-Methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl]methanesulfonamide serves as a versatile boronate building block for Suzuki-Miyaura cross-coupling reactions. The tetramethylboronate group enables efficient palladium-catalyzed coupling with aryl and heteroaryl halides under mild conditions. The methoxy and sulfonamide functionalities provide enhanced solubility, stability, and orthogonal reactivity, facilitating purification and downstream functionalization in medicinal chemistry and API synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: