Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

6-Fluoropyridazin-3-amine

  • CAS No. 108784-42-5

  • Cat. No. CS-0054088
  • Molecule weight113.09
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

6-Fluoropyridazin-3-amine|CS-0054088

Structure of 108784-42-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 108784-42-5
  • Cat. No. CS-0054088
  • Purity ≥97%
  • MDL No. None
  • Storage -20°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₄FN₃
  • Molecular Weight 113.09
  • Synonym(s) 3-AMino-6-fluoropyridazine
  • SMILES NC1=NN=C(F)C=C1

Description

6-Fluoropyridazin-3-amine features a fluorinated pyridazinone core with a primary amine at the 3-position, delivering enhanced electron-withdrawing character and improved metabolic stability. This scaffold integrates readily into bioactive molecules, serving as a key building block in medicinal chemistry for kinase inhibitors and CNS-targeted therapeutics.

Application

6-Fluoropyridazin-3-amine serves as a versatile building block in medicinal chemistry, enabling efficient access to bioactive heterocycles. The fluorine substituent enhances metabolic stability and modulates electronic properties, while the primary amine facilitates diverse coupling reactions. Its bench-stable nature and compatibility with standard synthetic protocols make it ideal for constructing kinase inhibitors and other pharmaceutical scaffolds.

Synthesis

  • Route1

    References

    • Barlin, Gordon B. Australian Journal of Chemistry, 1986 , vol. 39, # 11 p. 1803 - 1809
  • Route2
    • null|null
      1336-21-6
    • In-stock
      3,6-Difluoropyridazine|CS-W018931
      33097-39-1
    • ~%
    • In-stock
      6-Fluoropyridazin-3-amine|CS-0054088
      108784-42-5

    References

    • Takeda Chemical Industries, Ltd. Patent: US4864022 A1, 1989 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   51.8
  • LogP   0.1979
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 6-Fluoropyridazin-3-amine sigma6-Fluoropyridazin-3-amine manufacturer6-Fluoropyridazin-3-amine price6-Fluoropyridazin-3-amine structure6-Fluoropyridazin-3-amine SDSbuy 6-Fluoropyridazin-3-amine6-Fluoropyridazin-3-amine supplier6-Fluoropyridazin-3-amine uses6-Fluoropyridazin-3-amine molecular weightprice of 6-Fluoropyridazin-3-amine6-Fluoropyridazin-3-amine chemical name formula of 6-Fluoropyridazin-3-amine
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label