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Structure of 1093758-87-2
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2-Bromo-5-fluoropyridin-3-ol features a pyridine core functionalized with bromo and fluoro substituents at adjacent positions, enabling selective cross-coupling reactions. The phenolic hydroxyl group enhances polarity and facilitates derivatization, while the electron-deficient ring system supports nucleophilic substitution under mild conditions. This compound serves as a key building block in the synthesis of bioactive heterocycles and pharmaceutical intermediates.
2-Bromo-5-fluoropyridin-3-ol serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The bromine site facilitates efficient C–C bond formation, while the fluorine and hydroxyl groups offer strategic points for further functionalization or hydrogen bonding in target molecules. Bench-stable and compatible with standard purification methods, it functions reliably in the synthesis of heterocyclic scaffolds and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: