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*For research and further manufacturing use only, not for direct human use.
Structure of 109389-30-2
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DMT-dU-CE Phosphoramidite delivers a protected uridine derivative with a 5'-dimethoxytrityl group and a 3'-cholesteryl ether linkage, enabling efficient incorporation into oligonucleotides. The cholesteryl moiety enhances duplex stability through hydrophobic interactions, while the DMT group ensures convenient purification and monitoring. This reagent supports robust synthesis under standard conditions.
DMT-dU-CE Phosphoramidite serves as a key building block for the site-specific incorporation of 5-(2-cyanoethyl)-2'-deoxyuridine into oligonucleotides during solid-phase synthesis. Its cyanoethyl protecting group enables efficient deprotection under mild basic conditions, ensuring high fidelity and minimal side reactions. The dimethoxytrityl (DMT) group provides excellent UV monitoring and facilitates purification via chromatography. This phosphoramidite exhibits robust stability, predictable coupling efficiency, and broad compatibility with standard synthesis protocols, making it ideal for the preparation of modified DNA sequences in research and diagnostics.
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GHS Pictogram :
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GHS No : GHS08
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H317-H319-H335-H360
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: