3-(tert-Butyldimethylsilyloxy)propan-1-amine

Name: 3-(tert-Butyldimethylsilyloxy)propan-1-amine
Brand: ChemScene
Availability: InStock
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CAS No. 115306-75-7
Cat. No. CS-0139636
Purity≥95%
MDL No.MFCD18206137

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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3-(tert-Butyldimethylsilyloxy)propan-1-amine|CS-0139636

Structure of 115306-75-7

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Description

3-(tert-Butyldimethylsilyloxy)propan-1-amine features a silyl-protected hydroxyl group paired with a primary amine, enabling selective functionalization in complex molecule synthesis. This bench-stable derivative facilitates orthogonal protection strategies in organic and peptide chemistry workflows.

Application

3-(tert-Butyldimethylsilyloxy)propan-1-amine serves as a versatile silyl-protected amine building block, enabling stable storage and selective deprotection in multi-step syntheses. Its tert-butyldimethylsilyl (TBS) ether group provides excellent bench stability and orthogonal compatibility with common functional groups. The molecule facilitates efficient incorporation into complex scaffolds via standard coupling reactions, particularly useful in the synthesis of peptide analogs and bioactive heterocycles where controlled reactivity and purification ease are critical.

General Information

CAS No. 115306-75-7
Cat. No. CS-0139636
Purity ≥95%
MDL No. MFCD18206137
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₂₃NOSi
Molecular Weight 189.37
Synonym(s) None
SMILES O(CCCN)[Si](C)(C)C(C)(C)C

Computational Chemistry Data

TPSA 35.25
LogP 2.357
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 4

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Organosilicon compounds

Building Blocks Skeleton Fatty chain compounds

Material Science Organic-Inorganic Hybrid Materials A silane coupling agent

Chemical Synthesis Organometallic Reagents Organosilicon Organosilicon Compounds (Other)

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3-(tert-Butyldimethylsilyloxy)propan-1-amine

CAS No. 115306-75-7

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