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CS-W001157 4
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((S)-1-((R)-1-phenylethyl)pyrrolidin-3-yl)methanol

  • CAS No. 109960-55-6

  • Cat. No. CS-0440796
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

((S)-1-((R)-1-phenylethyl)pyrrolidin-3-yl)methanol|CS-0440796

Structure of 109960-55-6

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General Information

  • CAS No. 109960-55-6
  • Cat. No. CS-0440796
  • Purity ≥98%
  • MDL No. None
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₉NO
  • Molecular Weight 205.30
  • Synonym(s) (3S)-1-((R)-1-phenylethyl)-3-(hydroxymethyl)pyrrolidine
  • SMILES C[C@H](C1=CC=CC=C1)N2CC[C@@H](C2)CO

Synthesis

  • Route1
    • Methyl (3S)-5-oxo-1-[(1R)-1-phenylethyl]pyrrolidine-3-carboxylate|CS-0049277
      99735-46-3
    • ~85%
    • ((S)-1-((R)-1-phenylethyl)pyrrolidin-3-yl)methanol|CS-0440796
      109960-55-6

    References

    • Nielsen, Lone; Brehm, Lotte; Krogsgaard-Larsen, Povl Journal of Medicinal Chemistry, 1990 , vol. 33, # 1 p. 71 - 77
  • Route2
    • (S)-4-(Hydroxymethyl)-1-((R)-1-Phenylethyl)pyrrolidin-2-one|CS-0765707
      215183-32-7
    • ~85%
    • ((S)-1-((R)-1-phenylethyl)pyrrolidin-3-yl)methanol|CS-0440796
      109960-55-6

    References

    • Fava, Cristiana; Galeazzi, Roberta; Mobbili, Giovanna; Orena, Mario Heterocycles, 1999 , vol. 51, # 10 p. 2463 - 2470
  • Route3
    • 5-Oxo-1-((R)-1-phenylethyl)pyrrolidine-3-carboxylic acid|CS-0461706
      915302-94-2
    • ~%
    • ((S)-1-((R)-1-phenylethyl)pyrrolidin-3-yl)methanol|CS-0440796
      109960-55-6

    References

    • Journal of Medicinal Chemistry, , vol. 30, # 10 p. 1711 - 1715

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS06
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H301-H315-H318-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   23.47
  • LogP   2.0618
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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