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Structure of 1218935-60-4
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(R)-2-(2,5-Difluorophenyl)pyrrolidine hydrochloride is a chiral building block featuring a fluorinated aromatic ring and a stereodefined pyrrolidine core. This bench-stable salt delivers enhanced solubility and handling convenience in synthetic workflows. The para-fluorine substitution imparts favorable electronic and metabolic stability, while the (R)-configuration ensures precise stereocontrol in asymmetric synthesis. It integrates readily into pharmaceutical intermediates and functional materials.
(R)-2-(2,5-Difluorophenyl)pyrrolidine hydrochloride serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of bioactive molecules through established coupling and functionalization reactions. Its bench-stable hydrochloride salt form facilitates handling and purification, while the (R)-configured pyrrolidine core provides stereochemical control in target-directed synthesis. The 2,5-difluorophenyl moiety enhances metabolic stability and modulates electronic properties, making this scaffold particularly useful in developing CNS-targeted therapeutics and kinase inhibitors.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: