H-D-Phe(3-F)-OH

Name: H-D-Phe(3-F)-OH
Brand: ChemScene
Availability: InStock
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CAS No. 110117-84-5
Cat. No. CS-0011436
Purity≥98%
MDL No.MFCD00066449

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Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

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Description

H-D-Phe(3-F)-OH features a fluorinated phenylalanine residue with enhanced metabolic stability and improved membrane permeability. This analog integrates readily into peptide sequences during solid-phase synthesis, offering a robust tool for bioactive peptide design where resistance to degradation is critical.

Application

H-D-Phe(3-F)-OH serves as a valuable building block in peptide synthesis, enabling the incorporation of a fluorinated phenylalanine residue at the meta-position. The 3-fluorophenyl group enhances metabolic stability and modulates electronic properties, facilitating improved binding affinity in bioactive peptides. This derivative exhibits excellent bench stability, compatibility with standard coupling protocols, and simplifies purification due to distinct chromatographic behavior.

General Information

CAS No. 110117-84-5
Cat. No. CS-0011436
Purity ≥98%
MDL No. MFCD00066449
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₉H₁₀FNO₂
Molecular Weight 183.18
Synonym(s) None
SMILES FC1=CC(C[C@@H](N)C(O)=O)=CC=C1

Computational Chemistry Data

TPSA 63.32
LogP 0.7801
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 3

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Phenylalanine and derivatives

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

Key Words

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H-D-Phe(3-F)-OH

CAS No. 110117-84-5

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