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Structure of 1101173-77-6
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trans-Methyl 3-((tert-butoxycarbonyl)amino)cyclobutanecarboxylate features a rigid cyclobutane scaffold with stereochemically defined configuration, enabling precise control in asymmetric synthesis. The tert-butoxycarbonyl (Boc) group provides robust protection for the amine, while the methyl ester offers a handle for selective derivatization. This bench-stable, moisture-tolerant intermediate integrates seamlessly into peptide mimetics and cyclic peptidomimetic architectures.
trans-Methyl 3-((tert-butoxycarbonyl)amino)cyclobutanecarboxylate serves as a versatile chiral building block for the synthesis of cyclobutane-containing pharmaceutical intermediates. Its stable trans-configured cyclobutane core, combined with orthogonal protection of the amine (Boc) and ester functionalities, enables selective transformations in multistep sequences. The compound exhibits excellent bench stability and facilitates efficient purification, making it well-suited for scalable peptide-like and heterocyclic scaffold construction.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319
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Precautionary Statements : P264-P270-P280-P301+P310-P302+P352-P305+P351+P338-P330-P332+P313-P337+P313-P362+P364-P501
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Lot numbers can be found on the outside label of a product: