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CS-W001157 4
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5-Methoxy-1H-pyrazol-3-amine hydrochloride

  • CAS No. 110884-53-2

  • Cat. No. CS-0050450
  • Purity≥97%
  • MDL No.MFCD17392863
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Methoxy-1H-pyrazol-3-amine hydrochloride|CS-0050450

Structure of 110884-53-2

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Description

5-Methoxy-1H-pyrazol-3-amine hydrochloride features a pyrazole core with a methoxy group at the 5-position and a primary amine at the 3-position, delivering enhanced solubility and stability under standard conditions. This bench-stable derivative serves as a key intermediate in medicinal chemistry, enabling efficient coupling reactions and facilitating access to diverse heterocyclic scaffolds for drug discovery applications.

Application

5-Methoxy-1H-pyrazol-3-amine hydrochloride serves as a versatile building block for heterocyclic synthesis, enabling efficient access to substituted pyrazole scaffolds. Its amine functionality facilitates direct coupling reactions and derivatization under mild conditions, while the methoxy group provides orthogonal reactivity and enhanced solubility. The hydrochloride salt ensures excellent bench stability and ease of handling, making it well-suited for medicinal chemistry campaigns and API intermediate development.

General Information

  • CAS No. 110884-53-2
  • Cat. No. CS-0050450
  • Purity ≥97%
  • MDL No. MFCD17392863
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₈ClN₃O
  • Molecular Weight None
  • Synonym(s) 3-amino-5-methoxypyrazole hydrochloride
  • SMILES Cl.COC1=CC(N)=NN1

Computational Chemistry Data

  • TPSA   63.93
  • LogP   0.4223
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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