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Structure of 111079-46-0
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3-Iodo-1H-pyridin-2-one features a reactive iodine handle at the C3 position of a pyridinone scaffold, enabling direct coupling in cross-coupling reactions. The electron-deficient ring system enhances reactivity in palladium-catalyzed transformations, while the bench-stable nature supports reliable handling under standard conditions. This compound serves as a key building block for functionalized heterocycles in medicinal chemistry and materials science.
3-Iodo-1H-pyridin-2-one serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions to construct biologically relevant heterocyclic scaffolds. The iodide group provides high reactivity in Suzuki, Stille, and Negishi couplings, while the pyridinone core offers hydrogen-bonding capability and metabolic stability. Its bench-stable nature and compatibility with diverse functional groups facilitate efficient synthesis of drug candidates and macrocyclic compounds.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: