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Structure of 111454-71-8
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3-Bromoisoxazole is a bench-stable heterocyclic building block featuring a bromine atom at the 3-position, enabling direct functionalization in cross-coupling reactions. The isoxazole core provides electron-deficient character and structural rigidity, facilitating incorporation into pharmaceutical intermediates and agrochemical scaffolds.
3-Bromoisoxazole serves as a versatile heterocyclic building block in synthetic organic chemistry, enabling efficient access to substituted isoxazoles via palladium-catalyzed cross-coupling reactions. Its bromine substituent facilitates reliable C–C bond formation under standard Suzuki, Stille, and Negishi conditions, while the isoxazole core provides metabolic stability and favorable pharmacophoric properties. The compound exhibits excellent bench stability and ease of purification, making it well-suited for medicinal chemistry campaigns and process-scale synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: