5-Bromo-1-(2,2,2-trifluoro-ethyl)-1H-pyridin-2-one

Name: 5-Bromo-1-(2,2,2-trifluoro-ethyl)-1H-pyridin-2-one
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1114563-10-8
Cat. No. CS-0341661
Purity≥98%
MDL No.MFCD15474994

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Bromo-1-(2,2,2-trifluoro-ethyl)-1H-pyridin-2-one|CS-0341661

Structure of 1114563-10-8

Size

Price

Quantity

* Please select Quantity before adding items.

Description

5-Bromo-1-(2,2,2-trifluoroethyl)-1H-pyridin-2-one features a trifluoromethylated ethyl side chain that enhances metabolic stability and lipophilicity. The bromine substituent at the 5-position enables facile late-stage functionalization via cross-coupling. This pyridinone scaffold integrates readily into bioactive molecules, offering a robust platform for medicinal chemistry and materials synthesis under standard conditions.

Application

5-Bromo-1-(2,2,2-trifluoroethyl)-1H-pyridin-2-one serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its well-defined bromo functionality. The trifluoroethyl group enhances metabolic stability and modulates lipophilicity, while the pyridin-2-one core provides a robust scaffold for further functionalization. Its bench-stable nature and compatibility with standard coupling protocols facilitate efficient synthesis of complex heterocyclic architectures.

General Information

CAS No. 1114563-10-8
Cat. No. CS-0341661
Purity ≥98%
MDL No. MFCD15474994
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₅BrF₃NO
Molecular Weight 256.02
Synonym(s) 5-bromo-1-(2,2,2-trifluoroethyl)pyridin-2(1H)-one
SMILES C1=CC(=O)N(C=C1Br)CC(F)(F)F

Computational Chemistry Data

TPSA 22
LogP 2.1731
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H320-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

1114563-10-8 sigma1114563-10-8 manufacturer1114563-10-8 price1114563-10-8 structure1114563-10-8 SDSbuy 1114563-10-81114563-10-8 supplier1114563-10-8 uses1114563-10-8 molecular weightprice of 1114563-10-81114563-10-8 chemical name formula of 1114563-10-8

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

5-Bromo-1-(2,2,2-trifluoro-ethyl)-1H-pyridin-2-one

CAS No. 1114563-10-8

Recommended Products