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Structure of 111625-28-6
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This hydrazine-functionalized reagent integrates a (2-pyridyldithio)-PEG1 spacer for site-specific conjugation. The pyridyl disulfide moiety enables selective cleavage under reducing conditions, while the hydrazine group facilitates stable linkage to carbonyl-containing biomolecules. Ideal for bioconjugation workflows requiring orthogonal functionalization and controlled release.
(2-pyridyldithio)-PEG1-hydrazine serves as a versatile bifunctional linker for site-specific conjugation in synthetic biology and medicinal chemistry. The hydrazine group enables selective reaction with carbonyl functionalities, while the pyridyldithio moiety facilitates disulfide exchange under mild conditions. Its PEG1 spacer provides enhanced solubility and reduced steric hindrance, supporting efficient coupling and purification in peptide, protein, and antibody-drug conjugate workflows.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 1759
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H312-H315-H317-H318-H332-H412
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Precautionary Statements : P261-P264-P270-P271-P272-P273-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: