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Structure of 395083-14-4
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Potassium trifluoro(prop-1-en-2-yl)borate delivers a stable, moisture-tolerant boron source for cross-coupling reactions. The prop-1-en-2-yl group enables direct functionalization of aryl and heteroaryl halides via Suzuki-Miyaura protocols. This reagent integrates cleanly into synthetic workflows, offering high chemoselectivity and minimal byproduct formation under standard conditions.
Potassium trifluoro(prop-1-en-2-yl)borate serves as a stable, bench-ready boron reagent enabling efficient allylic trifluoromethylation via Suzuki-Miyaura cross-coupling. Its robust functional group tolerance and compatibility with diverse aryl and vinyl electrophiles facilitate the construction of fluorinated alkene motifs commonly found in pharmaceutical scaffolds. The reagent’s high chemoselectivity and ease of handling make it a practical choice for iterative C–C bond formation in medicinal chemistry workflows.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H314
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501
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Lot numbers can be found on the outside label of a product: