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CS-W001157 4
Total: USD 88.00

Potassium trifluoro(prop-1-en-2-yl)borate

  • CAS No. 395083-14-4

  • Cat. No. CS-W003763
  • Molecule weight147.98
  • Purity≥96%
  • MDL No.MFCD11052654

*For research and further manufacturing use only, not for direct human use.

Potassium trifluoro(prop-1-en-2-yl)borate|CS-W003763

Structure of 395083-14-4

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General Information

  • CAS No. 395083-14-4
  • Cat. No. CS-W003763
  • Purity ≥96%
  • MDL No. MFCD11052654
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₅BF₃K
  • Molecular Weight 147.98
  • Synonym(s) Potassiumisopropenyltrifluoroborate
  • SMILES [F-][B+3]([F-])([C-](C)=C)[F-].[K+]

Description

Potassium trifluoro(prop-1-en-2-yl)borate delivers a stable, moisture-tolerant boron source for cross-coupling reactions. The prop-1-en-2-yl group enables direct functionalization of aryl and heteroaryl halides via Suzuki-Miyaura protocols. This reagent integrates cleanly into synthetic workflows, offering high chemoselectivity and minimal byproduct formation under standard conditions.

Application

Potassium trifluoro(prop-1-en-2-yl)borate serves as a stable, bench-ready boron reagent enabling efficient allylic trifluoromethylation via Suzuki-Miyaura cross-coupling. Its robust functional group tolerance and compatibility with diverse aryl and vinyl electrophiles facilitate the construction of fluorinated alkene motifs commonly found in pharmaceutical scaffolds. The reagent’s high chemoselectivity and ease of handling make it a practical choice for iterative C–C bond formation in medicinal chemistry workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   N/A
  • LogP   N/A
  • H_Acceptors   N/A
  • H_Donors   N/A
  • Rotatable_Bonds   N/A

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