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Structure of 1117-37-9
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(E)-Ethyl 3-(dimethylamino)acrylate features a conjugated enamine system with enhanced electron density at the β-position, enabling efficient Michael addition reactions. This bench-stable, moisture-tolerant acrylate integrates readily into synthetic sequences requiring nucleophilic olefins, particularly in the construction of nitrogen-containing heterocycles and bioactive molecule scaffolds.
(E)-Ethyl 3-(dimethylamino)acrylate serves as a versatile Michael acceptor and enamine precursor in synthetic organic chemistry. Its conjugated enamide system enables reliable Diels-Alder cycloadditions, Knoevenagel condensations, and nucleophilic additions under mild conditions. The dimethylamino group enhances electrophilicity at the β-carbon, facilitating efficient coupling reactions with amines, thiols, and carbon nucleophiles. Bench-stable and readily purified by distillation, it functions as a key building block for heterocyclic scaffolds and functionalized intermediates in medicinal chemistry and materials synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H317
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Precautionary Statements : P261-P272-P280-P302+P352-P363-P501
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Lot numbers can be found on the outside label of a product: