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Structure of 112332-97-5
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Methyl 6-hydroxy-1H-indole-3-carboxylate features a hydroxyl group at the 6-position of the indole core, enhancing solubility and reactivity for downstream functionalization. The ester moiety enables selective transformations under mild conditions, while the electron-rich aromatic system supports conjugation in photoreactive or bioconjugation applications. This bench-stable intermediate is well-suited for synthetic access to medicinally relevant heterocycles.
Methyl 6-hydroxy-1H-indole-3-carboxylate serves as a versatile building block for indole-based scaffolds, enabling direct functionalization at the C6 position. The hydroxyl group facilitates further derivatization via esterification, etherification, or transition-metal-catalyzed coupling reactions. Its methyl ester functionality supports selective reduction or nucleophilic displacement, while the indole core exhibits excellent bench stability and compatibility with standard synthetic protocols. This compound functions effectively in the synthesis of bioactive heterocycles and natural product analogs.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: