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Structure of 131424-27-6
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Methyl 6-methoxy-1H-indole-3-carboxylate features a methoxy-substituted indole core with a strategically positioned ester group, enabling direct integration into heterocyclic synthesis. This bench-stable derivative delivers enhanced solubility and reactivity in transition-metal-catalyzed coupling processes, serving as a key scaffold for medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds.
Methyl 6-methoxy-1H-indole-3-carboxylate serves as a versatile building block for indole-based scaffolds, enabling efficient functionalization at the C3 position via cross-coupling and nucleophilic substitution reactions. The methyl ester group facilitates straightforward derivatization, while the 6-methoxy substituent provides electronic modulation and enhanced solubility. Bench-stable and compatible with standard synthetic workflows, it functions as a key intermediate in the construction of bioactive heterocycles and pharmaceutical candidates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P264-P280-P302+P352-P362
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Lot numbers can be found on the outside label of a product: