Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1-(tert-Butoxycarbonyl)-3-fluoroazetidine-3-carboxylic acid

  • CAS No. 1126650-67-6

  • Cat. No. CS-0003939
  • Purity≥95%
  • MDL No.MFCD15071784
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-(tert-Butoxycarbonyl)-3-fluoroazetidine-3-carboxylic acid|CS-0003939

Structure of 1126650-67-6

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

Description

1-(tert-Butoxycarbonyl)-3-fluoroazetidine-3-carboxylic acid features a strained azetidine ring bearing a fluorine atom at the 3-position and a tert-butoxycarbonyl protecting group. This configuration imparts enhanced metabolic stability and facilitates selective incorporation into peptide scaffolds. The compound serves as a key building block for fluorinated cyclic amino acids in medicinal chemistry and bioconjugation applications.

Application

1-(tert-Butoxycarbonyl)-3-fluoroazetidine-3-carboxylic acid serves as a stable, bench-ready building block for the synthesis of fluorinated azetidine-containing scaffolds. The tert-butyl carbamate group enables straightforward deprotection under mild acidic conditions, while the 3-fluoroazetidine core provides enhanced metabolic stability and conformational rigidity. It reacts efficiently in standard amide coupling protocols and functions as a key intermediate in the construction of bioactive heterocycles relevant to medicinal chemistry and process development.

General Information

  • CAS No. 1126650-67-6
  • Cat. No. CS-0003939
  • Purity ≥95%
  • MDL No. MFCD15071784
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₄FNO₄
  • Molecular Weight 219.21
  • Synonym(s) 3-Fluoro-1,3-azetidinedicarboxylicacid tert-butyl ester
  • SMILES O=C(C1(F)CN(C(OC(C)(C)C)=O)C1)O

Computational Chemistry Data

  • TPSA   66.84
  • LogP   1.03
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1126650-67-6 sigma1126650-67-6 manufacturer1126650-67-6 price1126650-67-6 structure1126650-67-6 SDSbuy 1126650-67-61126650-67-6 supplier1126650-67-6 uses1126650-67-6 molecular weightprice of 1126650-67-61126650-67-6 chemical name formula of 1126650-67-6
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label