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Structure of 887591-62-0
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1-Boc-3-methylazetidine-3-carboxylic acid features a sterically constrained azetidine core with a methyl group at the 3-position, enhancing metabolic stability. The Boc-protected carboxylic acid moiety enables facile deprotection under mild acidic conditions, allowing direct integration into peptide sequences or conjugation workflows. This bench-stable reagent supports efficient access to bioactive heterocycles in medicinal chemistry and fragment-based drug discovery.
1-Boc-3-methylazetidine-3-carboxylic acid serves as a stable, bench-ready building block for the synthesis of azetidine-containing pharmaceuticals and bioactive molecules. The Boc group provides excellent protection of the carboxylic acid while maintaining compatibility with standard peptide coupling conditions. The tertiary α-carbon enables direct functionalization and facilitates incorporation into diverse heterocyclic scaffolds, including those found in kinase inhibitors and CNS-targeted therapeutics.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P260-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P337+P313-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: