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Structure of 1127-08-8
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Cyclohexane-1,1-dicarboxylic acid features a rigid cyclohexane core with two carboxylic acid groups fused at the same carbon center, delivering high steric constraint and enhanced stability. This unique geminal diacid structure facilitates selective functionalization in synthetic routes requiring defined spatial orientation, particularly in macrocyclic and polycyclic systems.
Cyclohexane-1,1-dicarboxylic acid serves as a rigid, bifunctional building block for medicinal chemistry and materials science, enabling the construction of constrained heterocycles and macrocyclic architectures. Its geminal dicarboxylic acid motif offers high functional group tolerance and facilitates straightforward derivatization via esterification or amidation. The compound exhibits excellent bench stability and is readily purified by recrystallization, making it well-suited for scalable synthesis and process development.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 2811
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: