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CS-W001157 4
Total: USD 88.00

1,1-Diisopropoxycyclohexane

  • CAS No. 1132-95-2

  • Cat. No. CS-W015602
  • Molecule weight200.32
  • Purity≥95%
  • MDL No.MFCD00236381

*For research and further manufacturing use only, not for direct human use.

1,1-Diisopropoxycyclohexane|CS-W015602

Structure of 1132-95-2

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General Information

  • CAS No. 1132-95-2
  • Cat. No. CS-W015602
  • Purity ≥95%
  • MDL No. MFCD00236381
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₂₄O₂
  • Molecular Weight 200.32
  • Synonym(s) Cyclohexanone Diisopropylketal; 1,1-Diisopropoxycyclohexane
  • SMILES CC(OC1(OC(C)C)CCCCC1)C

Description

It is employed as a reactant involved in 1,4-conjugate addition reactions with ethenesulfonamides to form arylethanesulfonamides, Suzuki-Miyaura reactions with dibromotrifluoromethylbenzene, cross-coupling reactions with diazoesters3 or potassium cyanate. It is involved in the synthesis of biarylketones and phthalides and synthesis of inhibitors including PDE4 inhibitors6 among others.

Synthesis

  • Route1

    References

    • Ono, Fumiaki; Takenaka, Hirotaka; Eguchi, Yuko; Endo, Masato; Sato, Tsuneo Synlett, 2009 , # 3 p. 487 - 489
  • Route2
    • null|null
      108-94-1
    • null|null
      67-63-0
    • ~%
    • 1,1-Diisopropoxycyclohexane|CS-W015602
      1132-95-2

    References

    • Synthesis, , p. 419 - 420

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1760
Class : 8
Packing Group : Ⅱ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501

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Computational Chemistry Data

  • TPSA   18.46
  • LogP   3.4968
  • H_Acceptors   2
  • H_Donors   0
  • Rotatable_Bonds   4

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