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Structure of 113269-06-0
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4-Fluoro-5-nitrobenzene-1,2-diamine features a fluorinated aromatic core with complementary electron-withdrawing nitro and electron-donating amino groups. This strategic substitution pattern enables direct coupling in cross-coupling reactions and facilitates incorporation into functionalized scaffolds for pharmaceutical and materials applications.
4-Fluoro-5-nitrobenzene-1,2-diamine serves as a versatile building block for heterocyclic synthesis, enabling efficient access to substituted quinoline and isoquinoline scaffolds via cyclization reactions. The ortho-diamine functionality facilitates palladium-catalyzed coupling processes, while the fluorine and nitro groups offer orthogonal reactivity for downstream functionalization. Bench-stable and amenable to standard purification methods, it functions reliably in multi-step synthetic sequences for advanced pharmaceutical intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: