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Structure of 113486-06-9
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tert-Butyl (2-methylbut-3-yn-2-yl)carbamate is a bench-stable, moisture-tolerant protecting group for primary amines, featuring a sterically hindered tert-butyl carbamate moiety linked to a terminal alkyne. This combination enables efficient copper-catalyzed coupling reactions and facilitates orthogonal protection in complex molecule synthesis.
tert-Butyl (2-methylbut-3-yn-2-yl)carbamate serves as a stable, bench-friendly building block for alkyne-based transformations in synthetic organic chemistry. Its terminal alkyne functionality enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC) and other transition-metal-mediated coupling reactions. The tert-butyl carbamate group provides excellent stability under basic conditions and facilitates straightforward deprotection with acid, enabling sequential functionalization in complex molecule synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H303-H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P405-P501
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Lot numbers can be found on the outside label of a product: