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Structure of 1135131-50-8
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Bromo-PEG1-CH2COOH features a reactive bromo group flanked by a short PEG spacer and a carboxylic acid terminus. This bifunctional architecture enables site-specific conjugation in bioconjugation workflows, combining efficient coupling chemistry with enhanced solubility in aqueous systems.
Bromo-PEG1-CH₂COOH serves as a versatile bifunctional linker for conjugation and polymer functionalization. The bromo group enables efficient nucleophilic substitution with amines, while the carboxylic acid facilitates amide coupling or activation via standard reagents. This structure offers excellent bench stability, solubility in aqueous and organic media, and compatibility with diverse synthetic workflows, making it ideal for peptide-protein conjugates, antibody-drug conjugate (ADC) intermediates, and surface-functionalized materials.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3261
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Class : 8
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Packing Group : Ⅲ
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Hazard Statements : H302-H315-H318-H335
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Precautionary Statements : P261-P280-P302+P352
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Lot numbers can be found on the outside label of a product: