(R)-1-(2-Bromophenyl)ethanamine

Name: (R)-1-(2-Bromophenyl)ethanamine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 113974-24-6
Cat. No. CS-0000274
Purity≥98%
MDL No.MFCD06761910

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(R)-1-(2-Bromophenyl)ethanamine|CS-0000274

Structure of 113974-24-6

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Description

(R)-1-(2-Bromophenyl)ethanamine is a chiral amine featuring a brominated aromatic ring and a stereodefined ethylamine side chain. This configuration enables selective incorporation into asymmetric synthesis, particularly in the construction of pharmacologically active intermediates. The molecule exhibits enhanced stability under standard bench conditions and facilitates efficient coupling reactions in medicinal chemistry workflows.

Application

(R)-1-(2-Bromophenyl)ethanamine serves as a valuable chiral building block in medicinal chemistry, enabling the synthesis of asymmetric pharmaceutical intermediates. Its well-defined stereochemistry and brominated aryl group facilitate efficient transition-metal-catalyzed coupling reactions, including Suzuki and Negishi couplings. The compound exhibits good bench stability and is compatible with common protecting groups, making it suitable for multi-step synthetic sequences in API development.

General Information

CAS No. 113974-24-6
Cat. No. CS-0000274
Purity ≥98%
MDL No. MFCD06761910
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₀BrN
Molecular Weight 200.08
Synonym(s) =-1-(2-Bromophenyl)
SMILES BrC1=CC=CC=C1[C@@H](C)N

Computational Chemistry Data

TPSA 26.02
LogP 2.4688
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-1-(2-Bromophenyl)ethanamine

CAS No. 113974-24-6

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