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Structure of 114344-60-4
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2-Amino-3-bromobenzonitrile features a bromine atom at the meta position relative to an amino group, delivering enhanced reactivity in cross-coupling processes. The nitrile functionality provides a polar handle for downstream transformations, while the electron-rich aromatic core supports efficient metal-catalyzed functionalization. This bench-stable compound integrates readily into complex molecular architectures.
2-Amino-3-bromobenzonitrile serves as a versatile building block in medicinal chemistry and agrochemical synthesis, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal reactivity profile. The bromo group facilitates Suzuki, Stille, and Negishi couplings, while the amino and nitrile functionalities offer sites for further derivatization. Bench-stable and readily purified by recrystallization, it functions efficiently in multi-step syntheses of heterocyclic scaffolds and bioactive molecules.
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GHS Pictogram :
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GHS No : GHS06
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Signal Word : Danger
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UN#: 3439
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Class : 6.1
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Packing Group : Ⅲ
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Hazard Statements : H301-H315-H319-H335
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Precautionary Statements : P264-P270-P330-P405-P501
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Lot numbers can be found on the outside label of a product: