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Structure of 114435-86-8
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Fluoromethyl 4-methylbenzenesulfonate serves as a reactive sulfonate ester for C–H functionalization, featuring a fluoromethyl group that enables selective alkylation under mild conditions. The para-methyl substituent enhances electron density at the aromatic ring, improving stability and reactivity in cross-coupling processes. This bench-stable reagent facilitates efficient incorporation of fluoromethyl motifs into complex molecular architectures.
Fluoromethyl 4-methylbenzenesulfonate serves as a versatile sulfonate ester for the selective introduction of fluoromethyl groups into organic substrates. It functions reliably in nucleophilic substitution reactions, enabling efficient installation of the fluoromethyl moiety under mild conditions. The reagent exhibits good bench stability and facilitates clean transformations with high functional group tolerance, making it suitable for iterative synthesis workflows in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS05
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Signal Word : Danger
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UN#: 3265
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Class : 8
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Packing Group : Ⅱ
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Hazard Statements : H227-H302-H314-H317
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Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
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Lot numbers can be found on the outside label of a product: