Oxazolo[4,5-c]pyridin-2-amine

Name: Oxazolo[4,5-c]pyridin-2-amine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 114498-55-4
Cat. No. CS-0005597
Purity≥98%
MDL No.MFCD15526655

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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Oxazolo[4,5-c]pyridin-2-amine|CS-0005597

Structure of 114498-55-4

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Description

Oxazolo[4,5-c]pyridin-2-amine delivers a rigid, electron-rich heterocyclic scaffold ideal for medicinal chemistry applications. This bench-stable core integrates seamlessly into kinase inhibitors and targeted therapeutics, offering enhanced binding affinity through its planar structure and nitrogen-rich functionality.

Application

Oxazolo[4,5-c]pyridin-2-amine serves as a privileged heterocyclic scaffold in medicinal chemistry, enabling efficient access to bioactive molecules through its inherent nitrogen-rich architecture. The compound exhibits robust bench stability and functions as a versatile building block for late-stage functionalization, particularly in Suzuki-Miyaura and Buchwald-Hartwig couplings. Its moderate basicity and favorable solubility profile facilitate purification and integration into complex molecular frameworks relevant to kinase inhibitor and CNS-targeted drug discovery.

General Information

CAS No. 114498-55-4
Cat. No. CS-0005597
Purity ≥98%
MDL No. MFCD15526655
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₅N₃O
Molecular Weight 135.12
Synonym(s) Oxazolo[4,5-c]pyridin-2-amine (9CI)
SMILES NC(O1)=NC2=C1C=CN=C2

Computational Chemistry Data

TPSA 64.94
LogP 0.805
H_Acceptors 4
H_Donors 1
Rotatable_Bonds 0

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Oxazole compounds

Key Words

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Oxazolo[4,5-c]pyridin-2-amine

CAS No. 114498-55-4

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