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Methyl (S)-2-amino-3-((tert-butoxycarbonyl)amino)propanoate hydrochloride

  • CAS No. 114559-25-0

  • Cat. No. CS-0132955
  • Purity≥97%
  • MDL No.MFCD00798684

*For research and further manufacturing use only, not for direct human use.

Methyl (S)-2-amino-3-((tert-butoxycarbonyl)amino)propanoate hydrochloride|CS-0132955

Structure of 114559-25-0

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General Information

  • CAS No. 114559-25-0
  • Cat. No. CS-0132955
  • Purity ≥97%
  • MDL No. MFCD00798684
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₉ClN₂O₄
  • Molecular Weight 254.71
  • Synonym(s) (S)-Methyl 2-amino-3-((tert-butoxycarbonyl)amino)propanoate hydrochloride
  • SMILES N[C@@H](CNC(OC(C)(C)C)=O)C(OC)=O.[H]Cl

Description

Methyl (S)-2-amino-3-((tert-butoxycarbonyl)amino)propanoate hydrochloride is a bench-stable, moisture-tolerant chiral building block featuring a protected amino group and a methyl ester functionality. This configuration enables direct incorporation into peptide synthesis workflows without racemization, streamlining access to complex peptidomimetics and bioactive scaffolds under standard conditions.

Application

Methyl (S)-2-amino-3-((tert-butoxycarbonyl)amino)propanoate hydrochloride serves as a key chiral building block for peptide synthesis and heterocyclic scaffolds. The Boc-protected amine and ester functionalities enable orthogonal reactivity, facilitating sequential coupling and selective deprotection. Bench-stable and readily purified by recrystallization or chromatography, it functions effectively in standard SPPS protocols and asymmetric synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   90.65
  • LogP   0.4332
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   3

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