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Methyl (S)-2-amino-3-((tert-butoxycarbonyl)amino)propanoate hydrochloride

  • CAS No. 114559-25-0

  • Cat. No. CS-0132955
  • Purity≥97%
  • MDL No.MFCD00798684
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Methyl (S)-2-amino-3-((tert-butoxycarbonyl)amino)propanoate hydrochloride|CS-0132955

Structure of 114559-25-0

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Description

Methyl (S)-2-amino-3-((tert-butoxycarbonyl)amino)propanoate hydrochloride is a bench-stable, moisture-tolerant chiral building block featuring a protected amino group and a methyl ester functionality. This configuration enables direct incorporation into peptide synthesis workflows without racemization, streamlining access to complex peptidomimetics and bioactive scaffolds under standard conditions.

Application

Methyl (S)-2-amino-3-((tert-butoxycarbonyl)amino)propanoate hydrochloride serves as a key chiral building block for peptide synthesis and heterocyclic scaffolds. The Boc-protected amine and ester functionalities enable orthogonal reactivity, facilitating sequential coupling and selective deprotection. Bench-stable and readily purified by recrystallization or chromatography, it functions effectively in standard SPPS protocols and asymmetric synthesis workflows.

General Information

  • CAS No. 114559-25-0
  • Cat. No. CS-0132955
  • Purity ≥97%
  • MDL No. MFCD00798684
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₉ClN₂O₄
  • Molecular Weight 254.71
  • Synonym(s) (S)-Methyl 2-amino-3-((tert-butoxycarbonyl)amino)propanoate hydrochloride
  • SMILES N[C@@H](CNC(OC(C)(C)C)=O)C(OC)=O.[H]Cl

Computational Chemistry Data

  • TPSA   90.65
  • LogP   0.4332
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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