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BrettPhos Pd G1

  • CAS No. 1148148-01-9

  • Cat. No. CS-0035151
  • Molecule weight798.81
  • Purity≥98%
  • MDL No.MFCD12545956

*For research and further manufacturing use only, not for direct human use.

BrettPhos Pd G1|CS-0035151

Structure of 1148148-01-9

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General Information

  • CAS No. 1148148-01-9
  • Cat. No. CS-0035151
  • Purity ≥98%
  • MDL No. MFCD12545956
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄₃H₆₃ClNO₂PPd
  • Molecular Weight 798.81
  • Synonym(s) BrettPhos Palladacycle
  • SMILES Cl[Pd]1([NH2]CCC2=C1C=CC=C2)[P](C3CCCCC3)(C4CCCCC4)C5=C(OC)C=CC(OC)=C5C6=C(C(C)C)C=C(C(C)C)C=C6C(C)C

Description

BrettPhos Pd G1 is a palladium catalyst featuring a sterically hindered, electron-rich phosphine ligand that enables efficient cross-coupling reactions under mild conditions. This bench-stable complex delivers high activity in Suzuki-Miyaura and Negishi couplings, offering robust performance with sensitive substrates.

Application

BrettPhos Pd G1 serves as a highly effective palladium catalyst for cross-coupling reactions, enabling reliable C–C and C–heteroatom bond formation under mild conditions. Its robust performance in Suzuki-Miyaura, Negishi, and Stille couplings is attributed to the electron-rich BrettPhos ligand, which enhances reactivity and stability. Ideal for complex molecule synthesis, it offers excellent functional group tolerance and facilitates efficient purification, making it a preferred choice for industrial and academic R&D workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   30.49
  • LogP   11.3905
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   10

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